Breaking The Code Of The Mummies With NGS: A Hallowe'en Special!

Ancient Egyptians believed in the afterlife. For them, death was merely a passage from a temporary body into a permanent spiritual existence. However, the preservation of the physical body was crucial for a happy […]

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Mars and Venus: Are Academia and Industry So Different?

Mars and Venus:  Are Academia and Industry So Different? One of the less acknowledged perks of scientific and technical training is that these educational paths prepare you for a vast selection of career options.  […]

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The Cell: An Image Library-CCDB – Tutorial Part 5

This is the fifth in a continuing series of tutorials on getting the most from The Cell: An Image Library-CCDB. In this tutorial you will be introduced to the new Pivot View tool that […]

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How Does it Move? Interpreting Motion of an Object with the Mean-Squared Displacement

Stuff moves. It is useful to study how stuff moves, because motion analysis can tell us a lot about the object that is moving. For example, we can learn if an object’s motion is […]

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Career Advice for Scientists from Scientists

Developing a career in the biological sciences can be a daunting venture.  You must throw your heart and soul into your career and wait years before you know if you are going to be […]

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Beneath the Lab Coat – Why do Scientists get Inked?

In 2007, award winning science writer Carl Zimmer asked a seemingly marginal question on his blog – how common is it for scientists to tattoo themselves with images of their science? Over the next […]

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How To Fix Isolated And In Situ Primary Cells

Unlike immortalized cells lines, primary cells can only be kept in cell culture for a finite period of time, if at all. Therefore, you often need to obtain primary cells directly from an animal […]

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Focus on isoelectric focussing

Isoelectric focussing electrophoresis (IEF) of proteins is nowhere near as popular as its cousin – sodium dodecyl sulphate-polyacrylamide gel electrophoresis aka SDS-PAGE. While in both methods the proteins are denatured, IEF is a gel-based […]

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Laser Capture Microdissection: Get it Out!

Imagine you are studying a very interesting new protein. You know in which cell type the protein is expressed, yet that specific cell type constitutes only a small minority among a large collection of […]

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The Birth Of The Epitranscriptome: RNA Gets Methylated Too!

Most biologists are aware of chemical modification of DNA in the form of 5-methylcytosine (mC), the eponymous ‘5th base’. Moving to the 6th base The fields of epigenetics and epigenomics are increasingly having an impact […]

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