Keeping Track of Your Literature

Keeping track of the scientific literature you have read is just as important as reading it in the first place.  You want to have your key papers on hand for easy access.  This will […]

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This One’s Upside Down! Inverted and Stereo Microscopes in Bioscience Laboratories

Most of the microscopes you will encounter in your laboratories will be ‘upright’. In other words, they are assembled (from top to bottom) in the order of; eyepieces, objectives (on revolving nosepiece), stage, sub-stage […]

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How to scale up a PCR reaction

Scientific creativity and repetitive tasks do not go well together.  There is nothing worse than having to repeat the same task over and over again – I know somebody who quit science because of […]

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A quick tour around probe-based multiplexing qPCR

PCR has become the tool of choice for molecular diagnostics and is now a staple platform in any laboratory setting. The versatility of this method has led to a myriad of spin-off techniques, including […]

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10 Tips For Organizing Your Lab Book

Writing your lab book is easy to put off as it never seems quite as important as splitting your cells or running that gel. I’m sure, like me, you’ve said to yourself it’s fine […]

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Counterstaining for Immunohistochemistry: Choices, Choices…

When it comes to immunohistochemistry (IHC) we spend a big chunk of time figuring out which antibody to use and which concentrations to try, but how many of us take the time to think […]

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We are the Tail that Wags the Dog: Bacteria as the Dominant Life Form on Earth

Sometimes, those of us working in the biological sciences might just wonder why we're putting all that time and effort into studying whatever it is we study. For those of us working with bacteria, […]

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How to Read a Scientific Paper

Keeping up with the scientific literature in your field of interest is incredibly important. Not only does it keep you informed as to what your competitors have been working on, it will also help […]

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Immunohistochemistry Basics: Blocking Non-Specific Staining

Immunohistochemistry staining uses antibodies to detect epitopes for targeted staining and while this assay is easy in theory, in practice it is finicky! Achieving good immunohistochemistry signal-to-noise ratio involves many factors, including a good […]

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A Brief Survey of Plasmid Mapping and DNA Annotation Software

Plasmid mapping and DNA annotation software is pretty abundant these days. A quick Google search brings up dozens of hits – but how do you know which one to use? If you are like […]

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