An Objective View: What do These Abbreviations Mean on Microscope Objectives?

In one of the previous articles from the Microscopy and Imaging Channel, we took a look at ‘that other number’ which you’ll find on a microscope objective: namely numerical aperture. The information you’ll find […]

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How Irish Scientists Changed the World by Seán Duke

I have to be honest, I am Irish and I am a Scientist, so I guess I am a bit biased in reviewing this book. Biases notwithstanding, this is a fascinating book. How Irish […]

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What is Confocal Laser Scanning Microscopy?

Fluorescent microscopy not only makes our images look good, it also allows us to gain a better understanding of cells, structures and tissue. With confocal laser scanning microscopy (CLSM) we can find out even […]

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Introducing CyTOF: Cytometry of the Masses

Flow cytometry remains unparalleled as a single-cell analysis technology.  The ability to analyze 14 or more fluorescent parameters on a million cells or more allows for detailed understanding of complex biological processes. One limitation […]

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An Easy Way to Start Using R in Your Research: Exploratory Data Analysis

As you’ve probably kind of guessed from our previous articles Introducng R and the Basic R Tutorial, we think R programming language and R-studio are great tools for data analysis and figure production.  And […]

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Western Blot, ELISA or PCR; which technique should I use?

A pretty standard experiment in a molecular biology laboratory is where a scientist stimulates some cells/tissue with a stimulus of interest i.e. cytokine. They can then analyse the cellular response to the external stimulus and […]

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When Glycogen is not Your Friend – Isolating RNA from Glycogen-Rich Tissues

Bitesize Bio has had a lot to say about RNA isolation, mainly because it is one of the most anxiety-producing requirements for molecular biology; especially when you are first starting out (although isolating proteins […]

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Verhoeff-van Gieson Stain: A Special Histology Stain for Elastic Fibers

What is Verhoeff-van Gieson’s stain? Ira Van Gieson first described the Verhoeff-van Gieson (VVG) staining protocol in 1889 as a method of evaluating collagen fibers in neural tissue. Frederick Herman Verhoeff, an American surgeon […]

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You did a Co-IP…now what?

You spent the last few weeks tweaking your Co-immunoprecipitation conditions, testing different antibody/bead combinations, and sampling a panaply of solutions and FINALLY! You have your Co-immunoprecipitation (Co-IP) elution… Now what? Well, you have a […]

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Herzenberg and the Invention of the FACS Machine

The flow cytometer that we have all grown to know and love may have only come into its own in the 1990’s, but who would have known that the first cell sorter was invented […]

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