The Ten Lab Commandments: Or the Guide to a Happy Lab

I was lucky enough to do my PhD in an extremely friendly and well-organised lab.  In my opinion, these two key traits are required for a successful research experience. This environment, while appearing effortless, […]

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Back to the 80s: The Top Ten 80s Songs for Your Lab Playlist

It’s like, no duh…the decade of the Rubik’s cube, E.T., big hair and shoulder pads, is making a comeback. Like Rocky rising against Clubber Lang (“You ain’t so bad!”), the buoyant 80s is fighting […]

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Never Leave an Empty Seat – A Simple Rule to Increase Your Networking at Scientific Talks

One of the great things about being scientists is that we are lifelong learners.  Scientists go to a lot of seminars, meetings and conferences.  The traditional, hour-long seminar is also a great way to […]

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Advanced Sectioning Techniques: How to Section Difficult Tissues.

Has this ever been your experience: You lovingly harvest, fix and embed your tissue, only to have your tissue shatter, wrinkle or otherwise look horrible when you section it? Well, before you throw your […]

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A Guide for Solving Your Lab Math Problems

Math is an important part of lab life, from making solutions to calculating protein concentrations, and miscalculations can cause mayhem for your experiments. Therefore it is important that your math is right, or you […]

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A primer on Probe-based SNP genotyping

Single Nucleotide polymorphisms (SNPs), colloquially pronounced ‘snips’, are the most common type of genetic variation in people. By definition, a SNP represents a single nucleotide variation at a specific location in the genome that […]

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Ancient RNA: Does Next Generation Sequencing Offer a New Window into the Past?

The wonders of ancient DNA (‘aDNA’) have become so commonplace that they almost cease to amaze. At this point, we’ve sequenced the genomes of Neanderthals, woolly mammoths, and Pleistocene Cave Bears, and each week […]

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Seven Things That Really Annoy Me About Tissue Culture

The tissue culture facility can be one of the most important places in the lab.  Many researchers spend hours in the hoods isolating primary cell lines and tissue, generating samples for western blot analysis, […]

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Tissue Processing For Histology: What Exactly Happens?

A procedure which needs to take place between tissue fixation and the embedding/sectioning of paraffin blocks is tissue processing. You simply can’t take fixed tissue and embed it! We have already introduced fixation in […]

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My favorite laboratory Freebie

I love free stuff. Maybe it’s because I am from the former Soviet Union, where there wasn’t enough stuff around, let alone free. Or maybe a little happiness about getting something for nothing is […]

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