Counterstaining for Immunohistochemistry: Choices, Choices…

When it comes to immunohistochemistry (IHC) we spend a big chunk of time figuring out which antibody to use and which concentrations to try, but how many of us take the time to think […]

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We are the Tail that Wags the Dog: Bacteria as the Dominant Life Form on Earth

Sometimes, those of us working in the biological sciences might just wonder why we’re putting all that time and effort into studying whatever it is we study. For those of us working with bacteria, […]

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How to Read a Scientific Paper

Keeping up with the scientific literature in your field of interest is incredibly important. Not only does it keep you informed as to what your competitors have been working on, it will also help […]

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Immunohistochemistry Basics: Blocking Non-Specific Staining

Immunohistochemistry staining uses antibodies to detect epitopes for targeted staining and while this assay is easy in theory, in practice it is finicky! Achieving good immunohistochemistry signal-to-noise ratio involves many factors, including a good […]

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A Brief Survey of Plasmid Mapping and DNA Annotation Software

Plasmid mapping and DNA annotation software is pretty abundant these days. A quick Google search brings up dozens of hits – but how do you know which one to use? If you are like […]

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PCR is 30! Here’s How it has Rocked the World

This year marks an important birthday for molecular biologists: the polymerase chain reaction (PCR) turns 30!  This is my eulogy to celebrate life so far for the technique that has rocked the world. PCR […]

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Is it Worth Doing a PhD After a Masters?

This is a question that probably plagues every research student at some point in his/her career. The decision to pursue a PhD after getting your Masters degree is a difficult one.  A PhD is […]

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Haematoxylin and Eosin 101: Part Two- Recipes and Materials

Following on from the first part of the H and E 101 articles, here are the materials and recipes you’ll need for your own H and E workstation (assuming you don’t have access to […]

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What makes a good collaborator?

In its beginning science was a solitary pursuit: most of the papers in scientific journals prior to the 20th century have just one author.However, the change in scientific culture from “publish when you are […]

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The Irish Potato Famine: NGS Unearths The Fungus Responsible For Over 1 Million Deaths

The Irish Famine (or ‘Great Potato Famine’ if you live outside the Emerald Isle) killed one million people and forced another million to leave the country between 1845 and 1852. It was caused by […]

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