How to Switch Mentors, Part 3: Actually Switching – Is it Worth it?

Grad school is a big investment of your time, with a lot riding on a successful relationship with your mentor.  Unfortunately, you may have realized that the relationship is not working and resists improvement.  […]

view article

Gel Electro-For-Whatsit? Breaking Down How Gel Electrophoresis Works

Run to red!  It’s a mantra I learned when first using gel electrophoresis to separate DNA molecules.  This can save you a lot of frustration and humiliation in the lab (stage right: a complaining […]

view article

Analysing Microscopy Images? What You Should Know About Dynamic Range: Part 2

In the first part of this article (you can read it here), we looked at clipping and saturation in terms of microscope images, followed by a definition of Dynamic Range and an introduction to […]

view article

Get Your Proteins! Hot Proteins Here! Radioactively Labeled Proteins!

Radioactive protein labeling is not as common as it used to be. With the advent of modern protein labeling techniques, such as fluorescence, radioactive labeling has largely fallen out of favor. However, radioactive protein […]

view article

Chasing the Pot of Gold at the End of the Rainbow: Choosing the Right Fluorochromes for Your Flow Cytometry

With the current proliferation of new dyes and instruments that can detect many colors simultaneously, it seems like an entire rainbow is at your disposal for your flow cytometry experiments. And we know that […]

view article

5 Ways to Wreck Your Centrifuge

Surprise, surprise: That low frequency wobble isn’t your colleague’s dubstep. Before your centrifuge leaps off the bench and into a spirited dance, power down to see what’s the matter before it catastrophically destroys itself, […]

view article

Life or Death? Apoptosis in Healthy Organisms

Everybody has to die at some point. But fortunately, the death of a cell does not mean the end of the organism, at least for us metazoans. Indeed, controlled cell death a.k.a apoptosis, or […]

view article

Take Care of Your Tools: How to Clean a Pipette

Like a Jedi’s light saber, your pipette is an extension of your arm and the lifeline to your (lab) existence. You probably should give it a little TLC once in a while to keep […]

view article

Microbiology 101 by Aunt Yersinia

We are pleased to announce that the famous maid of microbiology, dear old Aunt Yersinia, has agreed to start writing a microbiology and molecular biology advice column for Bitesize Bio. She will be free […]

view article

How to Take a Cell Apart, i.e. How to Perform Subcellular Fractionation

I do not have to tell you that eukaryotic cells are not just sacks of homogeneous protoplasm. Instead the inside of all eukaryotic cells are divided into organelles and compartments, each with unique functions […]

view article
« Previous PageNext Page »

Article Categories