20 Ways to Increase your Productivity

No matter how efficient you are, it's always possible to improve your productivity and improving your productivity means that you get more of the rewards you are trying to obtain: results, publications… or dare […]

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Saying goodbye to 454: how to choose your next NGS platform

The Rise and Fall of the 454 Sequencer  The GS20 454 sequencer, released in 2005, was the first next-generation DNA sequencer to hit the market, and its feats quickly dazzled the scientific community. As […]

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PIER, HIER and Mannich: Antigen Retrieval in Immunohistochemistry

When you fix your tissue samples with paraformaldehyde (PFA) the proteins in your sample become covalently cross-linked. This is good to preserve the ‘architecture’ of your tissue sample. However, this cross-linking can become a […]

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Overview of Protein Turnover using 35S: how to prevent trashy data and uh-oh moments

The half-life of a protein is an important factor in many molecular biology studies. If your thesis has anything to do with proteins then your graduate advisory committee will ask about half-life, so start […]

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Christmas gifts for the scientist in your life

Christmas is fast approaching but if you haven't yet found the perfect gift never fear, there is still time! We’ve put together some of the most fabulous gifts for those of the science persuasion. […]

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All sorted? Getting the best out of your cell sorting facility

If you are bringing cells to a core to be sorted there are a few things you can do to optimise your sorting and will help the core staff. Here are a few hints: 1) Know […]

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5 Types of Bad Boss and How to Handle Them

Science attracts so many different and quirky personalities that you are bound to have a problem with some people. But when your boss is the problem, its a big problem for you. So what […]

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Microscope maintenance: changing and aligning your mercury burner

Mercury burners are one of the most common light sources used in fluorescence microscopes, producing a wide spectrum of wavelengths making them a great light source for viewing your samples. But they do have […]

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Cell Counting with a Hemocytometer: Easy as 1, 2, 3

Many biological applications such as microbiology, cell culture, blood work and many others that use cells require that we determine cell concentration for our experiment. Cell counting is rather straightforward and requires a counting […]

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The Basics: How Does DNA Ligation Work?

It takes a real effort to keep your basic knowledge of molecular and cell biology fresh, in addition to everything else you have to do. Wouldn't it be great to if there was a […]

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